A unique way to sort mixtures of active polymers on the basis of their length and activity is demonstrated.
Proteasome overexpression and proteasome-activating compounds alleviate AD-like pathology in cell culture, fly, and mouse models.
T cell–based immunotherapy destroys the tumor lymphatic vasculature to inhibit lymph node metastasis.
Mental health first responders successfully managed targeted police calls, reducing the reporting of and actual crime.
Midbrain dopamine neuron firing amplification by the calcium channel Cav1.3 suggests a treatment route for Parkinson disease.
Extremely dilute surface disorder on graphene can drive the formation of a long-range structural density wave phase.
Isogenic Alzheimer’s disease models are generated that are useful for development of drugs such as BACE1 inhibitors.
Neural network defines GBM features to be of neural crest perivascular or radial glia lineage.
Activator-inhibitor balance determines whether a nonlinear wave in live cells becomes a traveling wave or standing wave.
A subset of retinal ganglion cells responsible for non–image-forming vision is found to modulate visually guided eye growth.
Coactivation of reciprocal-inhibiting genes enables stabilized patterning during leaf and flower formation.
Many examples used in Taubes’ influential 1995 article to denigrate epidemiology now have important public health implications.
Brain controls blood glucose levels depending on nutrient states through the brain-periphery interaction.
Metamaterials can undergo stepwise, multimodal shape transformation.
Combining chemical imaging methods enables reconstruction of the original appearance of a degraded yellow rose in a still life.
An anion-pillared HUM realizes one-step C2H4 purification from ternary C2 hydrocarbon mixture by synergistic binding sites.
A universal mechanism for the Josephson diode effect in short superconducting junctions arises from finite Cooper pair momentum.
Fluid-mediated hydrodynamic interactions help synchronize and assemble microscopic particles driven with a ratchet effect.
Deregulating the shikimate pathway markedly increases aromatic amino acid production and carbon fixation in Arabidopsis.
Laser-induced phase separation enabled the rapid transformation of PEDOT:PSS into high-performance conductive hydrogels.
MIET-SMLM is a fluorescence lifetime–based approach to image subcellular structures with isotropic 3D super-resolution.
Pathway-based integration of multiomics and imaging assays maps physiological function of the human kidney at the single-cell level.
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