by Jonathan M. Werner, Jesse Gillis
Human neural organoids offer an exciting opportunity for studying inaccessible human-specific brain development; however, it remains unclear how precisely organoids recapitulate fetal/primary tissue biology. We characterize field-wide replicability and biological fidelity through a meta-analysis of single-cell RNA-sequencing data for first and second trimester human primary brain (2.95 million cells, 51 data sets) and neural organoids (1.59 million cells, 173 data sets). Читать дальше...
by Xin Yuan, Hailiang Li, Fang Guo
Organisms detect temperature signals through peripheral neurons, which relay them to central circadian networks to drive adaptive behaviors. Despite recent advances in Drosophila research, how circadian circuits integrate temperature cues with circadian signals to regulate sleep/wake patterns remains unclear. In this study, we used the FlyWire brain electron microscopy connectome to map neuronal connections, identifying lateral posterior neurons LPNs as... Читать дальше...
by Sarah Wettstadt, Francisco J. Marcos-Torres, Joaquín R. Otero-Asman, Alicia García-Puente, Álvaro Ortega, María A. Llamas
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by Rosanna C. T. Wright, A. Jamie Wood, Michael J. Bottery, Katie J. Muddiman, Steve Paterson, Ellie Harrison, Michael A. Brockhurst, James P. J. Hall
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by János Brunner, Antónia Arszovszki, Gergely Tarcsay, János Szabadics
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by Xitong Chen, Stephanie C. Leach, Juniper Hollis, Dillan Cellier, Kai Hwang
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by Xiaoyu Tian, Hanyu Wang, Song Liu, Wei Liu, Kaiyue Zhang, Xiaohan Gao, Qingchao Li, Huijie Zhao, Liangran Zhang, Peiwei Liu, Min Liu, Youjun Wang, Xueliang Zhu, Rutao Cui, Jun Zhou
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by Roy Novoselsky, Yotam Harnik, Oran Yakubovsky, Corine Katina, Yishai Levin, Keren Bahar Halpern, Niv Pencovich, Ido Nachmany, Shalev Itzkovitz
Читать дальше...The culmination of the 2024 presidential election between Vice President Kamala Harris and President-elect Donald Trump resulted in big numbers for Fox News and audience erosion for MSNBC and CNN. Trump's win was a big boon for FNC as it commanded the largest cable news share in its history with 62% of the cable news...
It's been a busy year for Disney Advertising and the company's streaming platforms. In 2024, Disney saw 40% of its total upfront dollars earmarked for streaming and digital offerings, and it has taken steps throughout the year to bolster that side of the business, including now working with nearly 40 demand-side platforms, making investments in...
Image: Bepi, Mio and MTM greet Mercury for the fifth time
The Ministry of Interior announced an increase in security measures ahead of the upcoming holiday season, focusing on the student celebrations on December 8, as well as the Christmas and New Year holidays. Law enforcement presence will be heightened in shopping centers and Christmas markets to deter serious criminal activity and ensure public safety. Additionally, extensive road checks will be conducted to address traffic-related incidents, including those caused by impaired drivers....
A year after graduating from college, Chi was adrift. She’d gone from a life of structure to one without guardrails and her mental health was declining. As a result, she distanced herself from friends and family. She left her job as a peer facilitator at a support group for people with depression and bipolar disorder […]
Italy is one of the growing number of countries with its own video game museum, as the GAMM game museum has opened in Rome.
Vector database pioneer is looking to dramatically improve enterprise AI accuracy with cascading retrieval innovations.
Couchbase integrates model serving, vectorization, agent catalog and enterprise AI function calling into its cloud database platform to help enterprises overcome deployment challenges.
Promoting better cybersecurity in an organization might mean doing things like locking user machines when they don't complete cyber training because accountability is not optional.
These 23 unforgettable TV characters deserve the NCIS: Origins backstory treatment -- because their untold pasts are just too good to ignore
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Tune in to AWS Partners LIVE!, streaming directly from AWS marquee events like re:Invent and re:Inforce, to catch all the breaking news and exclusive insights. Sponsored by AWS.
Читать дальше...A $28 billion merger in 2023 created Canadian Pacific Kansas City, which connects Mexico, the U.S. and Canada.
On October 16, 2024, hundreds of organizations and thousands of individuals across nearly 70 countries celebrated the 11th annual Global Ethics Day.
The designer channeled the brand’s ‘70s spirit into a youthful, instantly readable collection — and some not-to-be-missed accessories.
Keep the heat inside and your pipes flowing.