by Tingting Fan, Li Shao, Xingzhen Wang, Ping Ren
BackgroundHealthcare-associated infections (HAI) are a significant burden on the healthcare system. Recent research has suggested the role of copper in reducing HAI. The purpose of this study was to systematically search literature and pool data from studies evaluating the efficacy of copper-impregnated hospital linen in reducing HAI.
MethodsWe carried out a systematic electronic search of PubMed, ScienceDirect, BioMed Central, Springer... Читать дальше...
by Rebecca Brouwers, Hugh Vass, Angela Dawson, Tracey Squires, Sharareh Tavaddod, Rosalind J. Allen
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by Kyungreem Han, Richard W. Pastor, Cristina Fenollar–Ferrer
Interaction of phospholipase D2 (PLD2) with phosphatidylinositol (4,5)-bisphosphate (PIP2) is regarded as the critical step of numerous physiological processes. Here we build a full-length model of human PLD2 (hPLD2) combining template-based and ab initio modeling techniques and use microsecond all-atom molecular dynamics (MD) simulations of the protein in contact with a complex membrane to determine hPLD2-PIP2 interactions. MD... Читать дальше...
by Toshiyuki Aoyama, Yutaka Kohno
Muscle activity changes quantitatively and temporally during the motor learning process. However, the association between variability in muscle electrical activity and the learning and performance of dexterous hand movements is not well understood. Therefore, we undertook this study to investigate the relationships between temporal and quantitative variabilities in muscle activity and the learning of motor skills. Thirty-eight healthy participants performed... Читать дальше...
by Hannah F. Tavalire, Elizabeth L. Budd, Misaki N. Natsuaki, Jenae M. Neiderhiser, David Reiss, Daniel S. Shaw, Jody M. Ganiban, Leslie D. Leve
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by Priscila Neves-Silva, Juliana Aurora de Oliveira Lopes, Léo Heller
Access to water for rural populations is vital not only for personal consumption and hygiene but also for food production, income generation and cultural practices. To deepening the understanding of this issue, this research addressed the access to water in a settlement of the Landless Workers Movement. The perspective of the Human Rights to Water and Sanitation was used as a theoretical framework, assessing how inadequate... Читать дальше...
by Su-Jung Kim, Hyo-Won Ahn, Kyoung Jin Hwang, Sung-Wan Kim
ObjectiveTo investigate the frequency distribution of various craniofacial skeletal patterns in a large Korean adult obstructive sleep apnea (OSA) population, and to find a relationship between craniofacial risks and respiratory and sleep characteristics.
MethodsA total of 1226 OSA patients (mean age of 44.9±13.3 years) were included in this retrospective cross-sectional study. All subjects were evaluated for gender and age using fourteen polysomnographic... Читать дальше...
by Edwine W. Barasa, Paul O. Ouma, Emelda A. Okiro
IntroductionThe COVID-19 pandemic will test the capacity of health systems worldwide and especially so in low- and middle-income countries. The objective of this study was to assess the surge capacity of the Kenyan of the Kenyan health system in terms of general hospital and ICU beds in the face of the COVID-19 pandemic.
MethodsWe assumed that 2% of the Kenyan population get symptomatic infection by SARS-Cov-2 based on modelled... Читать дальше...
by Veronika Tirado, Josephine Chu, Claudia Hanson, Anna Mia Ekström, Anna Kågesten
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by Nalee Kim, Jin Sung Kim, Chang Geol Lee
PurposeWe evaluated that early metabolic response determined by 18F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) during radiotherapy (RT), predicts outcomes in non-small cell lung cancer.
Material and methodsTwenty-eight patients evaluated using pretreatment 18F-FDG-PET/CT (PETpre) and interim 18F-FDG-PET/CT (PETinterim) after 11 fractions of RT were retrospectively reviewed. Maximum standardized uptake... Читать дальше...
by Antonio Mancini, Carmine Bruno, Edoardo Vergani, Francesco Guidi, Flavia Angelini, Elisabetta Meucci, Andrea Silvestrini
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by João Conrado Khouri Dos-Santos, João Luiz Silva-Filho, Carla C. Judice, Ana Carolina Andrade Vitor Kayano, Júlio Aliberti, Ricardo Khouri, Diógenes S. de Lima, Helder Nakaya, Marcus Vinicius Guimarães Lacerda, Erich Vinicius De Paula, Stefanie Costa Pinto Lopes, Fabio Trindade Maranhão Costa
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by Zhengchen Su, Qing Chang, Aleksandra Drelich, Thomas Shelite, Barbara Judy, Yakun Liu, Jie Xiao, Changchen Zhou, Xi He, Yang Jin, Tais Saito, Shaojun Tang, Lynn Soong, Maki Wakamiya, Xiang Fang, Alexander Bukreyev, Thomas Ksiazek, William K. Russell, Bin Gong
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by Rule M. Budodo, Pius G. Horumpende, Sixbert I. Mkumbaye, Blandina T. Mmbaga, Richard S. Mwakapuja, Jaffu O. Chilongola
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by Claudia Mendonça Bezerra, Silvia Ermelinda Barbosa, Rita de Cássia Moreira de Souza, Levi Ximenes Feijão, Ricardo Esteban Gürtler, Alberto Novaes Ramos Jr, Liléia Diotaiuti
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by Vishal Goyal, Vidya Nand Rabi Das, Shambhu Nath Singh, Ravi Shankar Singh, Krishna Pandey, Neena Verma, Allen Hightower, Suman Rijal, Pradeep Das, Jorge Alvar, Caryn Bern, Fabiana Alves
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by Juan Rivera-Correa, Maria Fernanda Yasnot-Acosta, Nubia Catalina Tovar, María Camila Velasco-Pareja, Alice Easton, Ana Rodriguez
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by Keshava Mysore, Limb K. Hapairai, Longhua Sun, Ping Li, Chien-Wei Wang, Nicholas D. Scheel, Alexandra Lesnik, Jessica Igiede, Max P. Scheel, Na Wei, David W. Severson, Molly Duman-Scheel
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by Filip Z. Klawe, Thomas Stiehl, Peter Bastian, Christophe Gaillochet, Jan U. Lohmann, Anna Marciniak-Czochra
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by Solomon Shiferaw Beyene, Tianyi Ling, Blagoj Ristevski, Ming Chen
Riboswitch, a part of regulatory mRNA (50–250nt in length), has two main classes: aptamer and expression platform. One of the main challenges raised during the classification of riboswitch is imbalanced data. That is a circumstance in which the records of a sequences of one group are very small compared to the others. Such circumstances lead classifier to ignore minority group and emphasize on majority ones, which results in a skewed classification. Читать дальше...
by David R. Kelley
Machine learning algorithms trained to predict the regulatory activity of nucleic acid sequences have revealed principles of gene regulation and guided genetic variation analysis. While the human genome has been extensively annotated and studied, model organisms have been less explored. Model organism genomes offer both additional training sequences and unique annotations describing tissue and cell states unavailable in humans. Here, we develop a strategy to train deep... Читать дальше...
by Seung W. Ryu, Rose Stewart, D. Chase Pectol, Nicolette A. Ender, Oshadi Wimalarathne, Ji-Hoon Lee, Carlos P. Zanini, Antony Harvey, Jon M. Huibregtse, Peter Mueller, Tanya T. Paull
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by Jennifer N. Wells, Robert Buschauer, Timur Mackens-Kiani, Katharina Best, Hanna Kratzat, Otto Berninghausen, Thomas Becker, Wendy Gilbert, Jingdong Cheng, Roland Beckmann
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The TV star and her husband Liam Macauley – who only renewed their wedding vows in 2019 – separated earlier this year
LEEDS UNITED’S director of football Victor Orta is no dyed-in-the-wool Yorkshireman raised on tales of Don Revie, bitten legs and little black books. Although, as a former journalist and agent, the Spaniard certainly knows how it feels to be hated. And he clearly does understand Leeds. So as Leeds celebrated the end of a 16-year […]
