Disease ravaged the population. Thousands died and those who survived were forced to isolate themselves in their homes as medical officials attempted to purge the pestilence from the area. The economy, previously growing and sound, came to a standstill. Blame for the disaster was widespread, but it was an absence of leadership that bore the brunt of responsibility. The government officials charged with protecting the population were lax in preparation for a possible disaster and were often insufficient in their response to events.