"I'm only running the 200m here," said Jackson, the double world 200-metre champion, who has won silvers in the 100m in the last two world champs and Olympic 100m bronze at the Tokyo Games.
The 30-year-old did not give any details for her decision.
But Jackson's announcement does come in the wake of her pulling up with an apparent injury late in a race in Hungary three weeks ago.
The Jamaican was leading the race entering the home straight before abruptly slowing down, grimacing and putting her head in her hands as she eventually walked across the finish line.
Round one of the women's 100m at the Paris Olympics is scheduled for Friday at the Stade de France.
The semi-finals and final are programmed for Saturday.
The opening round for the 200m is due on Sunday, with semi-finals a day later and the final on Tuesday.
Jackson's teammate Elaine Thompson-Herah won both the 100 and 200m at the Tokyo Olympics.
