The matchup will be played on July 24 at Columbus, Ohio.
The MLS All-Stars beat their Liga MX rivals 2-1 in 2022 and 3-2 on penalties in 2021 in their prior meetings. Arsenal beat the MLS squad 5-0 in last year's All-Star Game.
"We're excited to host Liga MX at the 2024 MLS All-Star Game, showcasing the global and rising stars of our leagues and the strength of our sport in North America," said MLS executive vice president of properties and events Camilo Durana.
"Our previous encounters set high bars for intensity and competition in All-Star Games."
"We are very excited about the opportunity to reconnect and be close to the Mexican fanbase in the United States," Liga MX President Mikel Arriola said.
The MLS All-Star roster will include 12 players selected by fan voting, 12 more chosen by MLS All-Star head coach Wilfried Nancy, a Frenchman who is head coach of the reigning MLS champion Columbus Crew, and two players picked by MLS commissioner Don Garber.
