Food allergies affect millions of people worldwide, and flavonoids are promising natural compounds to help modulate the immune response and treat inflammation caused by these allergies. In a recent study, researchers have identified that kaempferol, a flavonoid, produces an anti-inflammatory effect through regulatory T-cell development. This occurred through increased RADLH2 expression in dendritic cells via AhR-mediated and PU.1/IRF-4 dependent mechanisms. Additionally, kaempferol suppressed several allergic symptoms in mice with food allergies.
