"The consequences of the Syrian war made Lebanon home to the largest number of refugees per capita, with one-third of our population comprising of Syrian refugees", Mikati said at a Rome political festival.
"The strain on our resources has been substantial, worsening existing economic trouble and creating fierce competition for jobs and services," he said in English.
"Today, and after the political transformation in Syria, the best resolution to this issue is for Syrians to go back to their homeland," he said.
Authorities say Lebanon, population 5.8 million, currently hosts around two million Syrians, while more than 800,000 are registered with the United Nations -- the highest number of refugees per capita in the world.
Many fled Syria after its civil war began following the repression of anti-government protests in 2011.
Mikati told a festival held by Italian Prime Minister Giorgia Meloni's Brothers of Italy party that "the international community, particularly Europe, should assist in the return of Syrians".
They should do so "by engaging in early recovery efforts in secure areas with Syria", he said.
