The helpline, known as the Reference Centre on Drug-Facilitated Sexual Assault (or CRAFS, its acronym in French), was launched by a Paris health centre on October 15.
That was in the middle of testimony at the rape trial of Dominique Pelicot and 50 other defendants, which has shocked the country, sparked mass protests and raised awareness in France about the use of drugs to commit abuse.
For years, Gisele Pelicot, Dominique's now-former wife, had strange memory lapses and other health problems, consulting numerous doctors who could not pinpoint the cause.
Then police told her she had been drugged and raped for nearly a decade by her husband and dozens of strangers he recruited online.
Since its launch, the helpline has received a wave of calls from healthcare providers and victims seeking information about drug-related abuse, said Leila Chaouachi, a doctor who founded the service.
"The doctors who contact us say they, too, might not have noticed anything," said Chaouachi, referring to Gisele Pelicot's symptoms.
"What are the warning signs? They feel they don't have enough training," she added.
Symptoms and guidance
One of the services offered by CRAFS is to provide information on the possible symptoms linked to drug-related abuse.
There are many indicators that someone could have been drugged, said Chaouachi: drowsiness, nausea, disorientation, blurred vision and amnesia, among others.
But some healthcare professionals tell Chaouachi they are worried they might overlook the signs or, if they do recognise them, are unsure of what to do next.
CRAFS can also offer guidance on those possible next steps.
One doctor who contacted the centre worried that a patient -- a victim of domestic violence -- was also drugged by her partner, and wanted to know if a hair analysis should be prescribed to detect the presence of substances.
"Five centimetres of hair is like five months of history," explained one of the CRAFS team of pharmacologists, who are also trained in sexual assault response.
Victims who call the hotline are encouraged to lodge a complaint to benefit from free drug detection kits.
In mid-November, Equality Minister Salima Saa announced an awareness campaign about the "new scourge" of using drugs to commit sexual abuse, which Chaouachi said can sometimes be misunderstood.
'Speaking out'
There are "preconceived notions" around the use of drugs in sexual assault cases, Chaouachi told AFP.
"People think it's about young girls drugged in a nightclub with GHB," said Chaouachi, referring to a notorious "date-rape drug" often used in sexual assaults.
"However, our data shows that the victim is often drugged by someone around her who betrays her trust," she said.
"It could be a woman of any age... an elderly person drugged to make them sign a paper extorting an inheritance, or a child drugged so someone doesn't have to look after them. That is chemical abuse."
In 2023, French police recorded more than 110,000 victims of sexual violence, 85 percent of them women.
For some, the hotline offers an opportunity to speak about what happened to them, even if the abuse was too long ago for medical detection.
"Even if they are old, these accounts are useful: they tell us how attackers operate," Chaouachi said. "And speaking out and being heard is good for the victim."
Prosecutors have sought a maximum 20-year jail term for Dominique Pelicot, and 10 to 18 years in prison for 49 of the 50 co-defendants accused of rape or attempted rape, with a four-year punishment requested in only one case.
A verdict is expected on December 19 or 20.
