A push-pull treatment for strengthening the ‘lazy eye’ in amblyopia

. Author manuscript; available in PMC: 2019 Apr 26.Published in final edited form as: Curr Biol. 2013 Apr 22;23(8):R309–R310. doi: 10.1016/j.cub.2013.03.004Teng Leng Ooi1, Yong R Su1, Danielle M Natale1, Zijiang J He2PMCID: PMC6485254NIHMSID: NIHMS967072PMID: 23618663The publisher's version of this article is available at Curr BiolAlmost all individuals exhibit sensory eye dominance, one neural basis of which is unequal interocular inhibition. Sensory eye dominance can impair binocular functions that depend on both excitatory and inhibitory mechanisms [1–3]. We developed a ‘push-pull’ perceptual learning protocol that simultaneously affects the excitatory and inhibitory networks to reduce sensory eye dominance and improve stereopsis in adults with otherwise normal vision [4]. The push-pull protocol provides a promising clinical paradigm for treating the extreme sensory eye dominance in amblyopia (‘lazy eye’). The prevailing standard of care does not directly treat sensory eye dominance...