Oral phenylephrine is sold as a nasal decongestant. It doesn't work very well, and the U.S. Food and Drug administration wants it removed from over-the-counter medications.
The agency conducted a comprehensive review of all available data on the safety and efficacy of oral phenylephrine, including the historical data that were used to support the determination made 30 years ago that oral phenylephrine was effective as a nasal decongestant, as well as newer clinical data on oral phenylephrine that have since become available.
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