by Maria Diamantaki, Athanasia Papoutsi
Bottom-up, data-driven, large-scale models provide a mechanistic understanding of neuronal functions. A new study in PLOS Biology builds a biologically realistic model of the rodent CA1 region that aims to become an accessible tool for the whole hippocampal community. Bottom-up, data-driven, large-scale models can provide a mechanistic understanding of neuronal functions. This Primer explores a new study in PLOS Biology that builds a biologically realistic model of the rodent CA1 region that aims to become an accessible tool for the whole hippocampus community.