On any cardiac electrophysiology service, the evaluation of survivors of resuscitated cardiac arrest is commonplace, often resulting in the placement of an implantable cardioverter-defibrillator, but without a satisfactory answer regarding the cause of the cardiac arrest. When a young and otherwise healthy family member of such a patient then dies suddenly, it is both tragic and frustrating, particularly if the family member was deemed in good health after a thorough cardiovascular assessment. Sadly, such a story has been the reality for more than 1 person with calcium release deficiency syndrome (CRDS).
