Even years after they have recovered, a person who once struggled with alcohol or opioid addiction can relapse--and that relapse is more likely to occur during particularly stressful times. Now, scientists have identified an area of the brain that plays a key role in stress-induced oxycodone relapse. Their findings explain why the drug suvorexant, which they previously found to reduce alcohol and oxycodone relapse when administered orally, works so well.