As described (more briefly) in the Hallmarks of Cancer section, metastasis is responsible for the great majority of deaths in cancer patients. This section details the steps by which cancer cells spread around the body and form new growths.Further information on the topics on this page can also be found in most introductory Biology textbooks, we recommend Campbell Biology, 11th edition.1Overview ofMetastasisFormation ofMetastasesRoutes ofMetastasisSpread of Cancer through the Lymphatic SystemHowMetastases Form New TumorsBarriers toMetastasisDrugs That Target MetastasisSection Summary: MetastasisTest your knowledge of how cancer spreads with an educational game:Know the Flow:MetastasisOverview ofMetastasisThe majority of deaths (about 90%) associated with cancer are due to the metastasis of the original tumor cells to sites distant from the initial or primary tumor. Metastasis is the process by which cancer cells migrate throughout the body.Exactly why cancer cells leave an initial site...
