People who spent much of their day at work sitting had a 16% higher risk of dying from any cause and a 34% higher mortality risk from cardiovascular disease compared with those who didn’t spend as much time sitting on the job, according to a cohort study in JAMA Network Open. After the study’s roughly 13-year surveillance of about 480 000 participants, researchers also found that people who mostly sat during the day but increased their physical activity by an extra 15 to 30 minutes had a similar chance of dying as sedentary individuals who did not spend as much time in a chair during the day.