Tumor cells circulating in the blood are the 'germ cells' of breast cancer metastases. They are very rare and could not be propagated in the culture dish until now, which made research into therapy resistance difficult. A team has now succeeded for the first time in cultivating stable tumor organoids directly from blood samples of breast cancer patients. Using these mini-tumors, the researchers were able to decipher a molecular signaling pathway that ensures the cancer cells' survival and resistance to therapy. Читать дальше...
Interactions with friends and family may keep us healthy because they boost our immune system and reduce our risk of diseases such as heart disease, stroke and type 2 diabetes, new research suggests. Researchers drew this conclusion after studying proteins from blood samples taken from over 42,000 adults recruited to the UK Biobank.
Each year, most species of bacteria in a Wisconsin lake rapidly evolved, apparently in response to dramatically changing seasons, and then evolved back.
EXCLUSIVE: At 17, Littler is going for glory once more on Friday night, when he takes on three-time champion Michael van Gerwen for the Sid Waddell Trophy at Alexandra Palace.
ROME: Napoli manager Antonio Conte remained confident in his team’s collective strength despite the absence of Khvicha Kvaratskhelia and Matteo Politano for today’s Serie A clash at Fiorentina.
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The Irish star, 28, admitted he was teased over his nose in secondary school
Families of hostages are subject to verbal and physical abuse while they demonstrate at the top of their voices at intersections.
The president wanted Jews out of the West Bank. The prime minister went only as far as the Sinai.
Where do you spend your time between work and home?
These informal social spaces are known as "third places," a term coined by sociologist Ray Oldenburg that refers to a wide array of spots people gather to socialize and pass time outside of their house or office.
In Chicago, there are plenty of "third places." Here are some of our readers' favorites, lightly edited for clarity:
"One of Chicago's excellent book shops, such as The Book Cellar or Unabridged Bookstore or the new Barnes & Noble in Wicker Park."
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Paul Mescal opened up in a new interview. The 28-year-old actor was selected as one of 16 stars to cover W Magazine’s Best Performances issue. In an accompanying interview, he reflected on his earliest memories of Gladiator, which came well before he was cast in the 2024 sequel. He also revealed a time that he [...]
Indian Parliament faces turbulent times in 2025 with the contentious One-Nation One-Election Bill and other key legislative matters. MPs will need to focus on people-centric issues and manage floor dynamics between BJP and Congress. Legislative priorities include the Union Budget, 129th constitution amendment Bill, Waqf Amendment Bill, and smooth functioning of Parliament to address public needs.
Parents seen holding sick children amid long queues in paediatric hospital units
Antibodies that bind to a previously untargeted portion of the malaria parasite could lead to new monoclonal antibody treatments and vaccines for malaria.
A study found public-private partnerships to develop, produce and distribute COVID-19 diagnostic tests saved approximately 1.4 million lives and prevented an estimated 7 million patient hospitalizations in the U.S. during the pandemic.
Researchers uncovered new findings about involuntary muscle movements that come with long-term administration of Parkinson's drug levodopa.
A new study has found that many cases of high-risk nonmetastatic hormone-sensitive prostate cancer may be more advanced than previously thought.
Over 8.6 million cars, trucks and SUVs were recalled in the U.S. last year, with Tesla leading all automakers with 5.1 million units affected.
In a bold move to secure their financial futures, Brazil’s leading airlines, Azul and Gol, have struck landmark agreements with the government to slash their tax debts by billions. This development marks a critical turning point for the country’s aviation sector, still reeling from pandemic-induced turbulence. Azul has successfully negotiated its R$2.5 billion ($0.4 billion) […]
Both General Motors and Ford reported their best annual U.S. new vehicle sales since 2019, prior to impacts from Covid and yearslong supply chain problems.
The undefeated middleweight sensation Khamzat Chimaev hasn't been seen in the cage since his stunning triumph over former UFC champion Robert Whittaker last year
The comedian thinks the far left isn’t ‘nearly as crazy as the crazies on the right’—but these days he focuses as much fire on the former.
Knobs, buttons, fun to drive, and up to 50 mpg means there's a lot to like.
