by Muhammad Bergas Nur Fayyad, Joeri R. Verbiest, Anna Ivanova, Mario Manto, Lousin Moumdjian
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by Florencia Grattarola, Hanna Shmagun, Christopher Erdmann, Anne Cambon-Thomsen, Mogens Thomsen, Jaesoo Kim, Laurence Mabile
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by Samina Sheikh, Anwar Ejaz Beg, Mirza Tasawer Baig, Sadaf Ibrahim, Ambreen Huma, Aisha Jabeen, Zubair Anwar
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by Hyun-Ho Kong, Kwangsoo Shin, Dong-Seok Yang, Aryun Kim, Hyeon-Seong Joo, Min Woo Oh, Jeonghwan Lee
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by Silje Nord-Baade, Ottar Ness, Camilla Bergsve Jensen, Michael Rowe, Elin Opheim, Anne Landheim
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by Taku Toyama, Ichiro Maruko, Han Peng Zhou, Miki Ikeda, Taiji Hasegawa, Tomohiro Iida, Makoto Aihara, Takashi Ueta
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by Huiqing Wang, Xiao Han, Shuaijun Niu, Hao Cheng, Jianxue Ren, Yimeng Duan
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by Xin Peng, Hantang Wang, Chunhui Guo, Ping Hu, Lei Xu, Jing Zhou, Zhirou Ding, Zhende Yang
by Xiao Li, Zhiquan Zhao
by Wilian Correa-Macedo, Monica Dallmann-Sauer, Marianna Orlova, Jeremy Manry, Vinicius M. Fava, Nguyen Thu Huong, Nguyen Ngoc Ba, Nguyen Van Thuc, Vu Hong Thai, Erwin Schurr
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by Sylvain Honoré Woromogo, Stéphanie Inesse Garoua-Adjou, Ange Donatien Ngouyombo, Rodrigue Herman Doyama-Woza, Henri Saint Calvaire Diemer, Jean de Dieu Longo
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by Tristan M. Lepage, Narcisse Nzune-Toche, Lucie A. Nkwengoua, Hugues C. Nana-Djeunga, Sebastien D. S. Pion, Joseph Kamgno, Charlotte Boullé, Jérémy T. Campillo, Michel Boussinesq, Claude T. Tayou, Cédric B. Chesnais
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by João Tiago Serra, Carina Silva, Mohsin Sidat, Silvana Belo, Pedro Ferreira, Natália Ferracini, Daniel Kaminstein, Ricardo Thompson, Claúdia Conceiçao
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by Emmanuel John Tabilin, Catherine A. Gordon, Yi Mu, Mario Jiz, Marianette Inobaya, Eleonor Avenido-Cervantes, Darren Gray, Mary Lorraine Mationg, Donald P. McManus, Thomas G. Egwang, Moses Adriko, Yasuhito Sako, Marcello Otake Sato, Megumi Sato, Hong You, Matthew Kelly, Pengfei Cai
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by Kelsey E. Grinde, Brian L. Browning, Alexander P. Reiner, Timothy A. Thornton, Sharon R. Browning
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by Wes Spiller, Jack Bowden, Eleanor Sanderson
BackgroundMendelian randomization (MR) is a statistical approach using genetic variants as instrumental variables to estimate causal effects of a single exposure on an outcome. Multivariable MR (MVMR) extends this to estimate the direct effect of multiple exposures simulatiously. MR and MVMR can be biased by the presence of pleiotropic genetic variants in the set used as instrumental variables, violating one of the core IV assumptions. Genetic... Читать дальше...
by Qinghe Li, Yuhong Liu, Yuanyuan Wang, Qi Zhang, Na Zhang, Danli Song, Fei Wang, Qianmei Gao, Yuxin Chen, Gaomeng Zhang, Jie Wen, Guiping Zhao, Li Chen, Yu Gao
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by Justine Guguin, Ting-Yu Chen, Silvestre Cuinat, Alicia Besson, Eloïse Bertiaux, Lucile Boutaud, Nolan Ardito, Miren Imaz Murguiondo, Sara Cabet, Virginie Hamel, Sophie Thomas, Bertrand Pain, Patrick Edery, Audrey Putoux, Tang K. Tang, Sylvie Mazoyer, Marion Delous
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by Henrik Zunker, René Schmieding, David Kerkmann, Alain Schengen, Sophie Diexer, Rafael Mikolajczyk, Michael Meyer-Hermann, Martin J. Kühn
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by Moritz Grosse-Wentrup, Akshey Kumar, Anja Meunier, Manuel Zimmer
Explaining how neuronal activity gives rise to cognition arguably remains the most significant challenge in cognitive neuroscience. We introduce neuro-cognitive multilevel causal modeling (NC-MCM), a framework that bridges the explanatory gap between neuronal activity and cognition by construing cognitive states as (behaviorally and dynamically) causally consistent abstractions of neuronal states. Multilevel causal modeling... Читать дальше...
by Thiago Ohno Bezerra, Antonio C. Roque
Astrocytes respond to neurotransmitters by increasing their intracellular Ca2+ concentration (Ca2+ signals). While glutamate released by neurons trigger Ca2+ signals through IP3- and glutamate transporter-dependent mechanisms, dopamine released in distant sites activates astrocytes via dopaminergic receptors. However, little is known about the modulatory effects of dopamine on glutamate-evoked astrocytic activity. To investigate this question, we developed multi-compartment... Читать дальше...
by Siwen Zhao, Xuguang Jiang, Ning Li, Tao Wang
Phospholipids are critical building blocks of mitochondria, and proper mitochondrial function and architecture rely on phospholipids that are primarily transported from the endoplasmic reticulum (ER). Here, we show that mitochondrial form and function rely on synthesis of phosphatidylserine (PS) in the ER through phosphatidylserine synthase (PSS), trafficking of PS from ER to mitochondria (and within mitochondria), and the conversion of PS to... Читать дальше...
by Xihui Xu, Jiandong Jiang
Bioremediation using synthetic microbiomes offers significant advantages over traditional single-strain-based approaches. In this Perspective, we outline 5 important considerations for the rational design of pollutant-degrading microbiomes for enhanced bioremediation. Bioremediation using synthetic microbiomes offers significant advantages over traditional single‐strain‐based approaches. In this Perspective, the authors outline five important considerations for... Читать дальше...
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