This study analyzes pharmacy benefit manager market concentration for commercial insurance, Medicare Part D, and Medicaid managed care in the US.
This Viewpoint explores recent US Supreme Court decisions and how they threaten the Emergency Medical Treatment and Labor Act and the health, safety, and rights of pregnant persons throughout the country.
This Viewpoint explores the various types of state laws establishing fetal personhood and the potential implications of these laws on health care, patients, and clinicians.
This Review summarizes current evidence on pathogenesis, epidemiology, diagnosis, and treatment of community-acquired pneumonia and focuses on adults without immune-compromising conditions.
The Review titled “Management of Depression in Adults: A Review,” published on June 10, 2024, was corrected to add missing absolute difference data in the Selection of First-Line Treatment subsection of the Discussion. This article was corrected online.
This Medical News article is an interview with Quarraisha Abdool Karim, PhD, and Salim S. Abdool Karim, MBChB, PhD, who received the award for their decades of work on AIDS in Africa.
This Viewpoint summarizes the role of the Patent Trial and Appeal Board (PTAB) in reforming the drug patent process to avoid erroneously granted patents; highlights how other reform efforts, such as the PREVAIL Act, actually weaken the PTAB; and suggests changes to strengthen the PTAB and promote generic availability and reduced health care costs.
This Viewpoint from the US Food and Drug Administration (FDA) summarizes a recent update to an FDA draft interchangeability guidance regarding the need for clinical switching studies to illustrate the FDA’s ongoing efforts to streamline the development of biosimilar medications that are in line with the latest science.
His eyes wash over families of fruit, crushed cardboard, sticky hands. The trick is to be molecular: a watermelon sick with jaundice is no good, mushy inside. Carries disease internal to itself. Like how cells hold instructions for their own death or how birds always know the way home. His eyes washed with chemical droplets and still unseeing. Like light flushed down the sink. Shade of white so brutal it could kill you. Choose the roundest, brightest fruit, says Appa. Glaucoma, from glausso, from glow... Читать дальше...
This quasi-experimental study evaluates the association between the distribution of rapid diagnostic tests for malaria and the management of febrile illness and mortality among children younger than 5 years of age in sub-Saharan African countries.
In Reply We recently reported that cardiovascular biomarkers were strongly associated with fatal and nonfatal cardiovascular events and mortality, but their addition to established risk factors resulted in only a small improvement in risk prediction metrics.
To the Editor A recent study that aimed to assess the prognostic value of routinely available cardiovascular biomarkers when added to established risk factors found that incorporating these biomarkers resulted in only a modest improvement in risk prediction metrics for atherosclerotic cardiovascular disease. However, the improvement was more notable for predicting heart failure and mortality. Despite these interesting results, several issues warrant further attention.
This cross-sectional study analyzes characteristics of prehospital encounters for youth opioid overdoses and trends before and during the COVID-19 pandemic.
This JAMA Insights in the Communicating Medicine series explores how differences in word choice can affect both visit interactions and visit outcomes in patient encounters.
Diagnosis is not the end, but the beginning of practice.Martin H. Fisher
In this narrative medicine essay, a pediatrician discusses the ambiguity of diagnoses of patients and settles on honestly admitting when the parameters are unclear with an explanation of the range of possibilities.
This JAMA Patient Page describes the autoimmune disease systemic lupus erythematosus and its symptoms, diagnosis, treatment, and prognosis.
Contrary to prevailing impression, medicine’s concern with ethical problems is not a by-product of recent advances in medical knowledge and skills. True, problems such as allotment of a limited organ supply among the many in need of a transplant or deciding to terminate an artificially sustained life did not exist in the past, but abortion, euthanasia, and other issues have always presented dilemmas. Some of these, such as the decision to save the life of a mother or the newborn, were even more frequent than they are now... Читать дальше...
Listen to the JAMA Editor’s Summary for an overview and discussion of the important articles appearing in JAMA.
The Review titled “Perioperative Management of Patients Taking Direct Oral Anticoagulants: A Review,” published on August 12, 2024, was corrected to fix several typographical errors in the last column of Table 1. This article was corrected online.
This Medical News article discusses the recent increase in parvovirus B19 infections in the US, resulting in a health advisory from the Centers for Disease Control and Prevention.
Immunotherapy drugs known as immune checkpoint inhibitors have improved long-term cancer survival rates by allowing a person’s immune system to attack tumor cells. But there has been concern about their role in inflammatory and autoimmune disorders, known as immune-related adverse events, that can include hypothyroidism, colitis, and diabetes.
Postmenopausal people who used hormone therapy (HT) displayed fewer signs of biological aging, according to an observational study published in JAMA Network Open. The researchers used data based on about 118 000 postmenopausal women with an average age of 60 years in the UK Biobank.
More than $558 million will go toward improving maternal health, the US Department of Health and Human Services (HHS) announced in August.
The number of heat-related deaths in the US has more than doubled in the past quarter century, increasing from roughly 1100 in 1999 to more than 2300 in 2023, a study in JAMA Network Open found. Heat-related mortality rates have been rising steadily since 2016, the researchers noted, with the highest number recorded in 2023, the hottest year on record.
