by Nancy Choudhary, Boas Pucker
BackgroundFlavonoids, an important class of specialized metabolites, are synthesized from phenylalanine and present in almost all plant species. Different branches of flavonoid biosynthesis lead to products like flavones, flavonols, anthocyanins, and proanthocyanidins. Dihydroflavonols form the branching point towards the production of non-colored flavonols via flavonol synthase (FLS) and colored anthocyanins via dihydroflavonol 4-reductase (DFR). Despite the wealth of publicly accessible data... Читать дальше...
by Gina T. Bryson, Dan G. O’Neill, Claire L. Brand, Zoe Belshaw, Rowena M. A. Packer
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by Xuanchun Huang, Lanshuo Hu, Shiyi Tao, Tiantian Xue, Jun Li, Xuejiao Wang
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by Amalia P. M. Bastos, Ashley Evenson, Patrick M. Wood, Zachary N. Houghton, Lucas Naranjo, Gabriella E. Smith, Alexandria Cairo-Evans, Lisa Korpos, Jack Terwilliger, Sarita Raghunath, Cassandra Paul, Hairou Hou, Federico Rossano
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by Carine Milcent, Hanta Ramaroson, Fleur Maury, Florence Binder-Foucard, Marie Moitry, Anne-Marie Moulin
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by Farah Waheed, Abdul Rashid, Asma Basit, Lubna Maroof
This study estimates the monetary policy reaction function (MPRF) in a Dynamic Stochastic General Equilibrium (DSGE) framework using Bayesian analysis for the emerging economies. DSGE models are suitable for the policy analysis because of their simplicity and prominent role of forward-looking variables. This is a pioneer study investigating the combined effects of credit spreads, fiscal imbalances, and monetary autonomy on interest rates for BRICS member countries. Читать дальше...
by Chiu-Feng Wu, Tzu-Pei Yeh, Tzu-Chen Lin, Po-Hsiang Huang, Pin-Jui Huang
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by Yiwen Jia, Guangming Feng, Tang Yang, Siyuan Chen, Fu Dai
Colon polyps have become a focal point of research due to their heightened potential to develop into appendiceal cancer, which has the highest mortality rate globally. Although numerous colon polyp segmentation methods have been developed using public polyp datasets, they tend to underperform on private datasets due to inconsistencies in data distribution and the difficulty of fine-tuning without annotations. In this paper, we propose... Читать дальше...
by Jackie Hamilton, Alice Welham, Gareth Morgan, Christopher Jones
ObjectivesThe focus of this review was to systematically review and meta-analyse the prevalence of ACEs among university students in the UK.
MethodThe systematic searching of six electronic databases (conducted February 2024) identified ten relevant articles (peer-reviewed articles of a quantitative nature that included ACE prevalence). PROSPERO reference: CRD42022364799.
ResultsPooled prevalence for number of ACEs endured was 55.4% (95% CI... Читать дальше...
by Yamei Liu
BackgroundThe increase in mental health problems among college students has become a global challenge, with anxiety and depression in particular becoming increasingly prevalent. Positive psychology has gained attention as an important psychological intervention that emphasizes improving mental health by promoting positive emotions and mindfulness. However, with the diversity of reading styles, however, there is a lack of systematic research on these effects. Therefore, this... Читать дальше...
by Fatih Özel, Marlene Stratmann, Fotios C. Papadopoulos, Joëlle Rüegg, Carl-Gustaf Bornehag
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by Elina Tsigeman, Viktoria Zemliak, Maxim Likhanov, Kostas A. Papageorgiou, Yulia Kovas
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by Richard T. Boylan
Inequality in economic and social outcomes across U.S. regions has grown in recent decades. The economic theory of crime predicts that this increased variability would raise geographic disparities in violent crime. Instead, I find that geographic disparities in homicide rates decreased. Moreover, these same decades saw decreases in the geographic disparities in policing, incarceration, and the share of the population that is African American. Thus, changes in policing... Читать дальше...
by Ciaran Michael Kelly, Russell Lewis McLaughlin
We present a comparison of machine learning methods for the prediction of four quantitative traits in Arabidopsis thaliana. High prediction accuracies were achieved on individuals grown under standardized laboratory conditions from the 1001 Arabidopsis Genomes Project. An existing body of evidence suggests that linear models may be impeded by their inability to make use of non-additive effects to explain phenotypic variation at the population level. Читать дальше...
by Jie Yin Chua, Ze Qin Lim, Song Qi Dennis Loy, Vanessa Koh, Natascha May Thevasagayam, Xiaowei Huan, Kyaw Zaw Linn, Kalisvar Marimuthu, Oon Tek Ng
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by Scott Selinger, Aneesh Thallapureddy
BackgroundFor two decades preceding the COVID-19 pandemic, testosterone therapy (TT) became more prevalent in the US. Given the forced shift in practice patterns and healthcare accessibility during the pandemic, it was unclear how TT utilization would change.
ObjectiveTo assess the change in testosterone prescriptions nationally.
DesignCross-sectional study.
Data sourcesState prescription drug monitoring program data between 2018 and 2022. Читать дальше...
by Shayeste Sadat Baghermanesh, Mahmood Barati, Arshad Hosseini
IntroductionPatients with breast cancer, especially triple-negative breast cancer, have a poor prognosis. There is still no effective treatment for this disease. Due to resistance to traditional treatments such as chemotherapy and radiation therapy, there is a need to discover novel treatment strategies to treat this disease. Ribociclib is a selective CDK4/6 inhibitor. Approximately 20% of patients with HR+ breast cancer developed primary resistance to CDK4/6 inhibitors... Читать дальше...
by Jale Boral, Cansel Vatansever, Gulin Ozcan, Siran Keske, Sirin Menekse, Mehmet Gonen, Fusun Can
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by Lucas Vega, Winslow Conneen, Michael A. Veronin, Robert P. Schumaker
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by Eun Jeong Won, Yu Jeong Lee, Moon-Ju Kim, Tae-Jong Kim, Hong-Joon Shin, Tae-Ok Kim, Yong-Soo Kwon
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by Iqra Akhtar, Shahid Atiq, Muhammad Umair Shahid, Ali Raza, Nagwan Abdel Samee, Maali Alabdulhafith
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by Veerakit Vanitshavit, Nisanart Charoenlap, Ratiboot Sallabhan, Wirongrong Whangsuk, Kisana Bhinija, Punyawee Dulyayangkul, Skorn Mongkolsuk, Paiboon Vattanavibooon
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by Aisha Fayomi, Sadaf Khan, Muhammad Hussain Tahir, Ali Algarni, Farrukh Jamal, Reman Abu-Shanab
by Isuru Liyanagama, Singeun Oh, Jun Ho Choi, Myung-hee Yi, Myungjun Kim, Sohyeon Yun, Dongjun Kang, Soo Lim Kim, Maria Gloria Ojeda Ayala, Fred Odua, Tai-Soon Yong, Ju Yeong Kim
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