by Ryuichiro Ishitani, Mizuki Takemoto, Kentaro Tomii
Ligand binding site prediction is a crucial initial step in structure-based drug discovery. Although several methods have been proposed previously, including those using geometry based and machine learning techniques, their accuracy is considered to be still insufficient. In this study, we introduce an approach that leverages a graph transformer neural network to rank the results of a geometry-based pocket detection method. We also created... Читать дальше...
by Giuseppe Chiossi, Riccardo Cuoghi Costantini, Daniela Menichini, Anna Luna Tramontano, Marialaura Diamanti, Fabio Facchinetti, Roberto D’Amico
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by Rongwang Guo, Jianxiu Wang, Yuntian You
Discrimination in the labor market hinders efficient labor allocation, impeding socio-economic health. With the rapid population aging in China, addressing multifaceted discrimination to enhance labor allocation efficiency emerges as a crucial area of research. To explore the relationship between five types of discrimination (age, gender, hukou, educational background, and occupation) and labor misallocation, this paper based on intersectionality theory... Читать дальше...
by Heping Xu, Yiqiao Liu, Huan Niu, Hong Wang, Feng Zhan
BackgroundEvidence associating body mass index (BMI) with the prognosis of Staphylococcus aureus sepsis remains scarce.
ObjectiveTo explore the association between BMI and clinical outcomes in intensive care units patients with Staphylococcus aureus sepsis.
MethodsA retrospective analysis of patients with Staphylococcus aureus sepsis was conducted using the MIMIC-IV database from the Critical Care Medicine Information. Читать дальше...
by Xun Liu, Yaqing Liu, Pengyan Xiong, Sixuan Guo, Lei Zhang, Li Liao
IntroductionRadiation exposure in medical settings stands as the primary source of artificial radiation, compounded by the yearly rise in healthcare worker numbers. Ensuring radiation protection is crucial for safeguarding their occupational health. Nevertheless, existing studies on radiation protection behavior exhibit considerable heterogeneity due to various factors.
ObjectiveThis scoping review aims to explore... Читать дальше...
by Alessandro Mirra, Claudia Spadavecchia, Olivier Levionnois
by Ahmed A. Albassam, Arwa N. Alenzi, Norah K. Alhaqbani, Fatimah K. Alhouty, Ziyad S. Almalki, Ahmed M. Alshehri, Hussain Aldossari, Muhammad Shahid Iqbal
by Jiaping Liu, Zhenglun Cai, Paul Gustafson, Daniel J. McDonald
To understand the transmissibility and spread of infectious diseases, epidemiologists turn to estimates of the instantaneous reproduction number. While many estimation approaches exist, their utility may be limited. Challenges of surveillance data collection, model assumptions that are unverifiable with data alone, and computationally inefficient frameworks are critical limitations for many existing approaches. We propose a... Читать дальше...
Known for its "finger-lickin' good" chicken and the secret recipe, KFC has become a global icon in the fast-food industry.
Artificial intelligence is here to stay. Here's how to learn all you can to move your business forward with artificial intelligence.
The Dinex Group CEO Sebastien Silvestri talks about the restaurant industry, diversification and true hospitality.
Filed under: Green,Chrysler,Jeep,Kia,Porsche,Toyota,Volvo,Crossover,Minivan/Van,SUV,Hybrid,Luxury,Sedan
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There are all kinds of fancy tools that I love, and then there are the basic tools that I use just about every day.
We reminded you of some modern electric cars that you probably forgot about last week, but this week we’re flipping to the new craze that’s sweeping the nation —hybrids. Hybrids are the new hot topic among profit-hungry car makers after buyers failed to swarm to overpriced EVs, but check these out before you go buy…
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Yet another contender has emerged for the title of Paris 2024's most stylish sport.
Nobody wants to leave heirs a confusing collection of files they can’t open, accounts they can’t access and assets they can’t locate.
As young people take up the old hobby of match collecting, matchbooks are taking on a new life as a badge of worldliness.
The device attaches to the shoulder bone and the tendon like the snake grabs its prey.
Darren Yamashita-USA TODAY Sports
Tuesday links!
Good morning, foLLks, and happy Tuesday!
In Mariners news:
AquaSox add trio of Modesto players to roster. Welcome to Everett INF Colt Emerson, RHP Gabriel Sosa, and LHP CJ Widger. pic.twitter.com/ltXlDXaFW4
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Neville E. Guard-USA TODAY Sports
MLB news roundup
Happy Tuesday Athletics Nation! Hope everyone’s week is going swimmingly.
We got a couple of positive updates regarding a pair of Oakland’s premier players on Monday afternoon, one on each side of the ball:
A’s injuries:
- Mason Miller threw 15 pitches in a live BP today and came away feeling healthy. Could be activated by the end of this series.
- Jacob Wilson is taking batting practice today. Making good... Читать дальше...
When we first see TikTok creator Ariel B (@the_arielb) in a recent clip, she’s holed up in the ladies’ room at Greenway Kia East car dealership in Orlando. She’s not happy at all.
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(Telecompaper) Viaplay is expanding its HVOD offer to Sweden, offering customers a cheaper price for its streaming service due to the inclusion of advertising...
