by Ahmed M. Abdou, Nanang R. Arifeta, Abdel-latif S. Seddek, Samy Abdel-Raouf Fahim Morad, Noha Abdelmageed, Mohamed O. Badry, Rika Umemiya-Shirafuji, Yoshifumi Nishikawa
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by Kosuke Oyama, Tadashi Ueda
Antigen-presenting cells (APCs) play a crucial role in the immune system by breaking down antigens into peptide fragments that subsequently bind to major histocompatibility complex (MHC) molecules. Previous studies indicate that stable proteins can impede CD4+ T cell stimulation by hindering antigen processing and presentation. Conversely, certain proteins require stabilization in order to activate the immune response. Several factors, including the characteristics... Читать дальше...
by Yuanjie Weng, Ryosuke Mega, Fumitaka Abe, Hisashi Tsujimoto, Masanori Okamoto
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by Thaisa Tylinski Sant’Ana, Sara Hanafy, Esme Fuller-Thomson, Michelle McDonald, Angela Colantonio, Daìthì Cee, Gráinne McGettrick, Brian Lawlor, Tatyana Mollayeva
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by Mohamad M. Saab, Megan McCarthy, Martin P. Davoren, Frances Shiely, Janas M. Harrington, Gillian W. Shorter, David Murphy, Billy O’Mahony, Eoghan Cooke, Aileen Murphy, Ann Kirby, Michael J. Rovito, Steve Robertson, Serena FitzGerald, Alan O’Connor, Mícheál O’Riordan, Josephine Hegarty, Darren Dahly
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by Patricia Perez-Bonilla, Brianna LaViolette, Bidur Bhandary, Soumya Ullas, Xian Chen, Dinesh Hirenallur-Shanthappa
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by Aline Alves de Souza, Stephano Tomaz da Silva, Lorenna Raquel Dantas de Macedo, Diogo Neres Aires, Karen de Medeiros Pondofe, Luciana Protásio de Melo, Ricardo Alexsandro de Medeiros Valentim, Tatiana Souza Ribeiro
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by Burcu Ünlütabak, Graciela Trujillo Hernandez, İlayda Velioğlu, David Menendez, Karl S. Rosengren
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by Ning Xie, Haixin Fan, Xiaochun Liu, Feng Ye, Zhenlin Weng
Using weekly data from January 2020 to December 2021 on the prices of various links in the Chinese broiler industry chain and the COVID-19 epidemic, we employed a time-varying parametric vector auto-regressive (TVP-VAR) model to investigate the dynamic effects of public health events on price fluctuations of upstream, midstream, and downstream products in the Chinese broiler industry chain. Our findings showed that the COVID-19... Читать дальше...
by Madan Khanal, Arjun Acharya, Rajesh Maharjan, Kalpana Gyawali, Rameshwar Adhikari, Deependra Das Mulmi, Tika Ram Lamichhane, Hari Prasad Lamichhane
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by Sheila Mukabana, Benta Abuya, Caroline W. Kabiru, Anthony Idowu Ajayi
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by Xiaolan Huang, Zhihua Du
RNA pseudoknots play a crucial role in various cellular functions. Established pseudoknots show significant variation in both size and structural complexity. Specifically, three-stemmed pseudoknots are characterized by an additional stem-loop embedded in their structure. Recent findings highlight these pseudoknots as bacterial riboswitches and potent stimulators for programmed ribosomal frameshifting in RNA viruses like SARS-CoV2. To investigate the possible presence... Читать дальше...
by Mireille Savoie, Aurora Mattison, Laurel Genge, Julie Nadeau, Sylwia Śliwińska-Wilczewska, Maximilian Berthold, Naaman M. Omar, Ondřej Prášil, Amanda M. Cockshutt, Douglas A. Campbell
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by Paola Adamo, Anna Fassi, Federico Temporiti, Davide De Leo, Giorgia Marino, Raffaello Furlan, Franca Barbic, Roberto Gatti, Isabella Barajon
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by Yao Liang, Osamu Maeda, Chiaki Kondo, Kazuki Nishida, Yuichi Ando
BackgroundThis study aimed to identify the associations between individual KRAS, STK11, KEAP1, or TP53 mutations, as well as the comutation status of these genes, and the tumor mutation burden (TMB) with clinical outcomes of lung adenocarcinoma patients treated with immune checkpoint inhibitors (ICIs).
MethodsWe collected data from patients with lung adenocarcinoma treated with ICIs from the Center for Cancer... Читать дальше...
by Yang Xiuyu, Tian Liyong, Cai Feng
As a key mechanism of belt conveyor, the health status and working state of its parts have a profound impact on whether the belt conveyor can run normally and safely. In the composition of the standard belt conveyor, the number of rollers is numerous and scattered. At the same time, under the complex environment of the work site, the fault detection of each roller is particularly difficult. In order to solve the above problems, a diagnosis method based... Читать дальше...
by Yihu Lei, Haibo Mu
Air-rail intermodal transportation (ARIT) plays a crucial role in China’s intermodal transportation system. This study aims to model and optimize issues such as inefficiency and complexity in China’s ARIT freight transportation using Business Process Reengineering and Stochastic Petri Nets theories. The Petri Net (PN) model for incoming freight transport in ARIT is based on actual operations, employing a new method involving Stochastic Petri Nets and isomorphic Markov Chains theory for performance analysis. Читать дальше...
by Sha Wan, Songhao Wang, Xianfei Yang, Yalan Cui, Heng Guan, Wenping Xiao, Fang Liu
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by Ibrahim Ali Ibrahim Muhina, Abid M. Sadiq, Fuad H. Said, Faryal M. Raza, Sarah K. Gharib, Sophia S. Muhali, Andrea R. Costantine, Mulhati S. Abdalla, Laura J. Shirima, Nyasatu G. Chamba, Furaha S. Lyamuya, Elifuraha W. Mkwizu, Kajiru G. Kilonzo, Venance P. Maro, Elichilia R. Shao
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by Mauricio Tano, Juha Baek, Adriana Ordonez, Rita Bosetti, Terri Menser, George Naufal, Bita Kash
by Tong Tong, Peifang Li, Haiwen Ding, Ying Huang, Sheng Liu
by Atenea Vázquez-Sánchez, Dalia Rodríguez-Ríos, Dannia Colín-Castelán, Jorge Molina-Torres, Enrique Ramírez-Chávez, Gloria del Carmen Romo-Morales, Silvio Zaina, Gertrud Lund
by Muhammad Nadeem, Saad H. Alotaibi, Fawziah M. Alotaibi, Yahya Alsayaad
by Miguel Costa-Gomes, Philipp Schoenegger
