by Nanbo Wang, Zhaohui Li, Lingling Cao, Zhihua Cui
ObjectiveThis study aimed to evaluate the effects of trilobatin (TLB) on dextran sulfate sodium (DSS)-induced ulcerative colitis (UC) in mice and further explore the underlying mechanisms from the perspectives of signaling pathway and gut microbiota.
MethodsA mouse model of UC was established using DSS. Trilobatin was administered via oral gavage. Disease severity was assessed based on body weight, disease activity index (DAI)... Читать дальше...
by Jia Hao Yeo, Jia Qian Low, Nasren Begam, Wan-Ting Leow, Andrea Lay-Hoon Kwa
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by M. Victoria Salgado, Joanne Penko, Alicia Fernández, Francine Rios-Fetchko, Pamela G. Coxson, Raúl Mejia
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by Gaizhen Liu, Qi Zhang, Meng Zhou, Baojie Li, Jianqi Zhao, Rui Bai, Xiaosu Song, Weiwei Qin, Yonglai Zhang
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by Mengjiao Zhao, Yongze Dong, Luchen Chen, Huajuan Shen
BackgroundStroke stands as a significant macrovascular complication among individuals with Type 2 diabetes mellitus (T2DM), often resulting in the primary cause of mortality and disability within this patient demographic. Presently, numerous studies have been conducted to investigate the underlying causes of stroke in individuals with T2DM, yet the findings exhibit inconsistencies.
ObjectiveThis paper aims to consolidate... Читать дальше...
by Rhiannon E. Cecil, Deborah R. Yoder-Himes
Exploration of interspecies interactions between microorganisms can have taxonomic, ecological, evolutionary, or medical applications. To better explore interactions between microorganisms it is important to establish the ideal conditions that ensure survival of all species involved. In this study, we sought to identify the ideal biotic and abiotic factors that would result in high co-culture viability of two interkingdom species, Pseudomonas aeruginosa and Acanthamoeba castellanii... Читать дальше...
by Yongqi Yu, Zexin Chi, Yanfeng Yu, Junjie Zhao, Liulin Peng
Agricultural socialized service is gradually emerging as a new stimulus for enhancing the agricultural production environment. However, their precise impact on improving the agricultural ecological environment and promoting the green development of agriculture remains incompletely understood. Therefore, leveraging panel data spanning from 2003 to 2020 across 31 provinces in China, this study utilizes the bidirectional fixed effect model... Читать дальше...
by Wenzhi Zhao, Xu Xie, Tian He, Jintao Zhang, Jiufen Liu
The adsorption and desorption of phosphorus (P) in soil constitute a crucial internal cycle that is closely associated with soil fertility, exerting direct influence on the quantity, form, and availability of P within the soil. The vertical spatial variation characteristics of soil adsorption and desorption were investigated for the 0–100 cm soil layer in the northeast black soil region in this study. The maximum adsorption capacity... Читать дальше...
by Jennifer J. Lee, Mavra Ahmed, Alena (Praneet) Ng, Christine Mulligan, Nadia Flexner, Mary R. L’Abbé
by Amy E. Galena, Jianmin Chai, Jiangchao Zhao, Michele Bednarzyk, Doreen Perez, Judith D. Ochrietor, Alireza Jahan-Mihan, Andrea Y. Arikawa
by Noah Parker
West Nile virus (WNV) is the most common mosquito-borne disease in the United States, resulting in hundreds of reported cases yearly in California alone. The transmission cycle occurs mostly in birds and mosquitoes, making meteorological conditions, such as temperature, especially important to transmission characteristics. Given that future increases in temperature are all but inevitable due to worldwide climate change, determining associations between temperature and WNV incidence in humans... Читать дальше...
by Josephine Bourner, Esteban Garcia-Gallo, Festus Mbrenga, Yap Boum II, Emmanuel Nakouné, Amy Paterson, Benjamin Jones, Piero Olliaro, Amanda Rojek
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by Faisal Ahmmed, Farhana Khanam, Md Taufiqul Islam, Deok Ryun Kim, Sophie Kang, Md Golam Firoj, Asma Binte Aziz, Masuma Hoque, Xinxue Liu, Hyon Jin Jeon, Suman Kanungo, Fahima Chowdhury, Ashraful Islam Khan, Khalequ Zaman, Florian Marks, Jerome H. Kim, Firdausi Qadri, John D. Clemens, Birkneh Tilahun Tadesse, Justin Im
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by José María Eloy Contreras-Ortiz, Daniel Hernández-Mendoza, Claudia Márquez-Dueñas, Rebeca Manning-Cela, Moisés Santillán
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by Stephen R. Walsh, Cynthia L. Gay, Shelly T. Karuna, Ollivier Hyrien, Timothy Skalland, Kenneth H. Mayer, Magdalena E. Sobieszczyk, Lindsey R. Baden, Paul A. Goepfert, Carlos del Rio, Guiseppe Pantaleo, Philip Andrew, Carissa Karg, Zonglin He, Huiyin Lu, Carmen A. Paez, Jane A. G. Baumblatt, Laura L. Polakowski, Wairimu Chege, Maija A. Anderson, Sophie Janto, Xue Han, Yunda Huang, Julie Dumond, Margaret E. Ackerman, Adrian B. McDermott, Britta Flach, Estelle Piwowar-Manning, Kelly Seaton, Georgia D. Читать дальше...
by Miriam Samuel, Robin Y. Park, Sophie V. Eastwood, Fabiola Eto, Caroline E. Morton, Daniel Stow, Sebastian Bacon, Amir Mehrkar, Jessica Morley, Iain Dillingham, Peter Inglesby, William J. Hulme, Kamlesh Khunti, Rohini Mathur, Jonathan Valabhji, Brian MacKenna, Sarah Finer, The OpenSAFELY Collaborative
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by Clio Hockens, Hernan Lorenzi, Tricia T. Wang, Elissa P. Lei, Leah F. Rosin
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by Ashutosh K. Rai, Katsuhiro Sawasato, Haley C. Bennett, Anastasiia Kozlova, Genevieve C. Sparagna, Mikhail Bogdanov, Angela M. Mitchell
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by Jared Adolf-Bryfogle, Jason W. Labonte, John C. Kraft, Maxim Shapovalov, Sebastian Raemisch, Thomas Lütteke, Frank DiMaio, Christopher D. Bahl, Jesper Pallesen, Neil P. King, Jeffrey J. Gray, Daniel W. Kulp, William R. Schief
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by Lara S. Burchardt, Yana van de Sande, Mounia Kehy, Marco Gamba, Andrea Ravignani, Wim Pouw
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by Leopold Zehetner, Diana Széliová, Barbara Kraus, Juan A. Hernandez Bort, Jürgen Zanghellini
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by Hyeonuk Woo, Yubeen Kim, Chaok Seok
As of now, more than 60 years have passed since the first determination of protein structures through crystallography, and a significant portion of protein structures can be predicted by computers. This is due to the groundbreaking enhancement in protein structure prediction achieved through neural network training utilizing extensive sequence and structure data. However, substantial challenges persist in structure prediction due to limited data availability... Читать дальше...
by Praveen Kumar Viswanathan, Aline Chessel, Maria Dolores Molina, Emmanuel Haillot, Thierry Lepage
Читать дальше...Choosing the right Chromebook for your needs can be a tough decision. We can help with our favorite picks.
In conjunction with the release of the Italian builder's new Tourbillon supercar comes an avant-garde watch.