by Joongbum Cho, Hyejeong Park, Danbee Kang, Esther Park, Chi Ryang Chung, Juhee Cho, Sapna R. Kudchadkar
Читать дальше...
by Simon Crase, Suresh N. Thennadil
Cluster analysis is a valuable unsupervised machine learning technique that is applied in a multitude of domains to identify similarities or clusters in unlabelled data. However, its performance is dependent of the characteristics of the data it is being applied to. There is no universally best clustering algorithm, and hence, there are numerous clustering algorithms available with different performance characteristics. This raises the problem of how to... Читать дальше...
by Béla P. Frohn, Tobias Härtel, Jürgen Cox, Petra Schwille
The Endosomal Sorting Complex Required for Transport (ESCRT) system is a multi-protein machinery that is involved in cell division of both Eukaryotes and Archaea. This spread across domains of life suggests that a precursor ESCRT machinery existed already at an evolutionary early stage of life, making it a promising candidate for the (re)construction of a minimal cell division machinery. There are, however, only few experimental data about ESCRT machineries in Archaea... Читать дальше...
by Kathryn Mazurek, Wei Xue, Marissa Beldon
PurposeThe passage of the Affordable Care Act in the US resulted in more Americans with health insurance coverage as well as expanded health benefits. However, barriers in accessing health care still exist in the US especially as it relates to some of the most vulnerable Americans including those with depressive disorders. The purpose of this cross-sectional secondary data analysis was to examine the differences in health-related quality of life... Читать дальше...
by Majidul Islam, Abdulrahman Al-Hashimi, Mosa Ayshasiddeka, Hanif Ali, Hesham Ali El Enshasy, Daniel Joe Dailin, R. Z. Sayyed, Tanzima Yeasmin
Читать дальше...
by Yu-Hsin Tang, Po-Liang Lu, Ho-Yin Huang, Ying-Chi Lin
BackgroundDiabetic patients are at risk of severe urinary tract infections (UTIs). Due to the emerging resistance rates to fluoroquinolones and β-lactams, we aimed to evaluate the effectiveness of β-lactams versus fluoroquinolones as empirical therapy for diabetic patients hospitalized for UTIs.
MethodsA retrospective cohort study was conducted in a medical center in Taiwan between 2016 and 2018. Patients with type 2 diabetes... Читать дальше...
by Mirzakamol S. Ayubov, Zabardast T. Buriev, Mukhammadjon K. Mirzakhmedov, Abdurakhmon N. Yusupov, Dilshod E. Usmanov, Shukhrat E. Shermatov, Khurshida A. Ubaydullaeva, Ibrokhim Y. Abdurakhmonov
Читать дальше...
by Wiebke Hartmann, Marie-Luise Brunn, Nadine Stetter, Gülsah Gabriel, Minka Breloer
Читать дальше...
by Lisa A. de Jong, Jessie Groeneveld, Jelena Stevanovic, Harrie Rila, Robert G. Tieleman, Menno V. Huisman, Maarten J. Postma, Marinus van Hulst
by Yukuto Sato, Idam Hermawan, Tetsuya Kakita, Sho Okano, Hideyuki Imai, Hiroto Nagai, Ryosuke Kimura, Tetsu Yamashiro, Tadashi Kajita, Claudia Toma
Читать дальше...
by Julio A. Benavides, Ram K. Raghavan, Vanner Boere, Silene Rocha, Marcelo Y. Wada, Alexander Vargas, Fernanda Voietta, Ita de Oliveira e Silva, Silvana Leal, Alene de Castro, Maria de Fatima Arruda, A. Townsend Peterson, Jane Megid, Maria Luiza Carrieri, Ivanete Kotait
Читать дальше...
by Carlos Bravo-Vega, Mauricio Santos-Vega, Juan Manuel Cordovez
The role of climate driving zoonotic diseases’ population dynamics has typically been addressed via retrospective analyses of national aggregated incidence records. A central question in epidemiology has been whether seasonal and interannual cycles are driven by climate variation or generated by socioeconomic factors. Here, we use compartmental models to quantify the role of rainfall and temperature in the dynamics of snakebite... Читать дальше...
by Stephanie N. Tornberg-Belanger, Doreen Rwigi, Michael Mugo, Lynnete Kitheka, Nancy Onamu, Derrick Ounga, Mame M. Diakhate, Hannah E. Atlas, Anna Wald, R. Scott McClelland, Olusegun O. Soge, Kirkby D. Tickell, Samuel Kariuki, Benson O. Singa, Judd L. Walson, Patricia B. Pavlinac
Читать дальше...
by Nol Salcedo, Ankita Reddy, Adam R. Gomez, Irene Bosch, Bobby Brooke Herrera
Читать дальше...
by David Peris, Dabao Sun Lu, Vilde Bruhn Kinneberg, Ine-Susanne Methlie, Malin Stapnes Dahl, Timothy Y. James, Håvard Kauserud, Inger Skrede
Читать дальше...
by Grant R. Howard, Tyler A. Jost, Thomas E. Yankeelov, Amy Brock
While acquired chemoresistance is recognized as a key challenge to treating many types of cancer, the dynamics with which drug sensitivity changes after exposure are poorly characterized. Most chemotherapeutic regimens call for repeated dosing at regular intervals, and if drug sensitivity changes on a similar time scale then the treatment interval could be optimized to improve treatment performance. Theoretical work suggests that such optimal schedules exist... Читать дальше...
by Laurel Fogarty, Madeleine Ammar, Thomas Holding, Adam Powell, Anne Kandler
by Pablo M. De Salazar, Fred Lu, James A Hay, Diana Gómez-Barroso, Pablo Fernández-Navarro, Elena V Martínez, Jenaro Astray-Mochales, Rocío Amillategui, Ana García-Fulgueiras, Maria D Chirlaque, Alonso Sánchez-Migallón, Amparo Larrauri, María J Sierra, Marc Lipsitch, Fernando Simón, Mauricio Santillana, Miguel A Hernán
Читать дальше...
by Elizabeth T. Bartom, Masha Kocherginsky, Bidur Paudel, Aparajitha Vaidyanathan, Ashley Haluck-Kangas, Monal Patel, Kaitlyn L. O’Shea, Andrea E. Murmann, Marcus E. Peter
Читать дальше...
by Jacqueline Scholl, Hailey A. Trier, Matthew F. S. Rushworth, Nils Kolling
Читать дальше...
by Erica L. Gorenberg, Sofia Massaro Tieze, Betül Yücel, Helen R. Zhao, Vicky Chou, Gregory S. Wirak, Susumu Tomita, TuKiet T. Lam, Sreeganga S. Chandra
Читать дальше...
by Kyung Ku Jang, Maria E. Kaczmarek, Simone Dallari, Ying-Han Chen, Takuya Tada, Jordan Axelrad, Nathaniel R. Landau, Kenneth A. Stapleford, Ken Cadwell
Читать дальше...
by Kristina Li, Shogo Wada, Bridget S. Gosis, Chelsea Thorsheim, Paige Loose, Zolt Arany
Читать дальше...