by Ozden Hatirnaz Ng, Sezer Akyoney, Ilayda Sahin, Huseyin Okan Soykam, Gunseli Bayram Akcapinar, Ozkan Ozdemir, Derya Dilek Kancagi, Gozde Sir Karakus, Bulut Yurtsever, Ayse Sesin Kocagoz, Ercument Ovali, Ugur Ozbek
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by Qi Song, Yourui Huang, Wenhao Lai, Tao Han, Shanyong XU, Xue Rong
This research proposes a new multi-membrane search algorithm (MSA) based on cell biological behavior. Cell secretion protein behavior and cell division and fusion strategy are the main inspirations for the algorithm. In order to verify the performance of the algorithm, we used 19 benchmark functions to compare the MSA test results with MVO, GWO, MFO and ALO. The number of iterations of each algorithm on each benchmark function is 100... Читать дальше...
by Clara Rimmer, Savas Hetelekides, Sophia I. Eliseeva, Steve N. Georas, Janelle M. Veazey
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by Lavanya Rajendran, Namita Khandelwal, Jocelyne Feine, Effie Ioannidou
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by Patricia K. Palmer, Kathryn Wehrmeyer, Marianne P. Florian, Charles Raison, Ellen Idler, Jennifer S. Mascaro
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by Megersa Girma Garo, Sileshi Garoma Abe, Worku Dugasa Girsha, Dawit Wolde Daka
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by Haijuan Yan, Xiaofei Hu, Dawei Wu, Jianing Zhang
Green development is an effective way to achieve economic growth and social development in a harmonious, sustainable, and efficient manner. Although the Yangtze River Economic Belt (YREB) plays an important strategic role in China, our understanding of its spatiotemporal characteristics, as well as the multiple factors affecting its green development level (GDL), remains limited. This study used the entropy weight method (EWM) to analyze... Читать дальше...
by Calum Marr, Eleftheria Vaportzis, Malwina A. Niechcial, Michaela Dewar, Alan J. Gow
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by Albert Mugenyi, Dennis Muhanguzi, Guy Hendrickx, Gaëlle Nicolas, Charles Waiswa, Steve Torr, Susan Christina Welburn, Peter M. Atkinson
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by Liliana Sánchez-González, Laura E. Adams, Rafael Saavedra, Emma M. Little, Nicole A. Medina, Chelsea G. Major, Marina Bruck, Julieanne Miranda, Coral Rosado-Santiago, Kyle Ryff, Marianyoly Ortiz, Grayson Brown, Roberto Barrera, Carmen L. Pérez-Guerra, Vanessa Rivera-Amill, Gabriela Paz-Bailey
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by Bruno Oliveira de Figueiredo Brito, Zachi I. Attia, Larissa Natany A. Martins, Pablo Perel, Maria Carmo P. Nunes, Ester Cerdeira Sabino, Clareci Silva Cardoso, Ariela Mota Ferreira, Paulo R. Gomes, Antonio Luiz Pinho Ribeiro, Francisco Lopez-Jimenez
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by Hannes Vietzen, Svenja Hartenberger, Stephan W. Aberle, Elisabeth Puchhammer-Stöckl
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by Eranga Sanjeewa Wijewickrama, Fahim Mohamed, Indika B. Gawarammana, Zoltan H. Endre, Nicholas A. Buckley, Geoffrey K. Isbister
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by Shelly Karuna, Shuying Sue Li, Shannon Grant, Stephen R. Walsh, Ian Frank, Martin Casapia, Meg Trahey, Ollivier Hyrien, Leigh Fisher, Maurine D. Miner, April K. Randhawa, Laura Polakowski, James G. Kublin, Lawrence Corey, David Montefiori, for the HVTN 405/HPTN 1901 Study Team
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by Hilary T. Brewis, Alice Y. Wang, Aline Gaub, Justine J. Lau, Peter C. Stirling, Michael S. Kobor
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by Manuel Albanese, Yen-Fu Adam Chen, Corinna Hüls, Kathrin Gärtner, Takanobu Tagawa, Ernesto Mejias-Perez, Oliver T. Keppler, Christine Göbel, Reinhard Zeidler, Mikhail Shein, Anne K. Schütz, Wolfgang Hammerschmidt
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by Naotaka Ochi, Mai Nakamura, Rina Nagata, Naoki Wakasa, Ryosuke Nakano, Tatsushi Igaki
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by Icíar Civantos-Gómez, Javier García-Algarra, David García-Callejas, Javier Galeano, Oscar Godoy, Ignasi Bartomeus
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by Ondrej Maxian, Raúl P. Peláez, Alex Mogilner, Aleksandar Donev
Cross-linked actin networks are the primary component of the cell cytoskeleton and have been the subject of numerous experimental and modeling studies. While these studies have demonstrated that the networks are viscoelastic materials, evolving from elastic solids on short timescales to viscous fluids on long ones, questions remain about the duration of each asymptotic regime, the role of the surrounding fluid, and the behavior of the networks on intermediate timescales. Читать дальше...
by Fu-Lai Wen, Chun Wai Kwan, Yu-Chiun Wang, Tatsuo Shibata
Epithelial tissues form folded structures during embryonic development and organogenesis. Whereas substantial efforts have been devoted to identifying mechanical and biochemical mechanisms that induce folding, whether and how their interplay synergistically shapes epithelial folds remains poorly understood. Here we propose a mechano–biochemical model for dorsal fold formation in the early Drosophila embryo, an epithelial folding event induced by shifts of cell polarity. Читать дальше...
by Francesco Mottes, Chiara Villa, Matteo Osella, Michele Caselle
This work studies the effects of the two rounds of Whole Genome Duplication (WGD) at the origin of the vertebrate lineage on the architecture of the human gene regulatory networks. We integrate information on transcriptional regulation, miRNA regulation, and protein-protein interactions to comparatively analyse the role of WGD and Small Scale Duplications (SSD) in the structural properties of the resulting multilayer network. Читать дальше...
by Lou Zonca, David Holcman
Rhythmic neuronal network activity underlies brain oscillations. To investigate how connected neuronal networks contribute to the emergence of the α-band and to the regulation of Up and Down states, we study a model based on synaptic short-term depression-facilitation with afterhyperpolarization (AHP). We found that the α-band is generated by the network behavior near the attractor of the Up-state. Coupling inhibitory and excitatory networks by reciprocal connections... Читать дальше...
by Md Ashfaq Ahmed, Sharmila Venugopal, Ranu Jung
Peristalsis, the coordinated contraction—relaxation of the muscles of the stomach is important for normal gastric motility and is impaired in motility disorders. Coordinated electrical depolarizations that originate and propagate within a network of interconnected layers of interstitial cells of Cajal (ICC) and smooth muscle (SM) cells of the stomach wall as a slow-wave, underly peristalsis. Normally, the gastric slow-wave oscillates with a single period and uniform rostrocaudal lag... Читать дальше...
by Stefano Longobardi, Anna Sher, Steven A. Niederer
Heart failure with preserved ejection fraction (HFpEF) is a complex disease associated with multiple co-morbidities, where impaired cardiac mechanics are often the end effect. At the cellular level, cardiac mechanics can be pharmacologically manipulated by altering calcium signalling and the sarcomere. However, the link between cellular level modulations and whole organ pump function is incompletely understood. Our goal is to develop and... Читать дальше...
by Lei Liu, Bokai Zhang, Changbong Hyeon
There is a growing realization that multi-way chromatin contacts formed in chromosome structures are fundamental units of gene regulation. However, due to the paucity and complexity of such contacts, it is challenging to detect and identify them using experiments. Based on an assumption that chromosome structures can be mapped onto a network of Gaussian polymer, here we derive analytic expressions for n-body contact probabilities (n > 2) among chromatin... Читать дальше...