by Michael S. Anderson, Nancy A. Niemuth, Carol L. Sabourin, Christopher S. Badorrek, Callie E. Bounds, Thomas L. Rudge Jr.
Читать дальше...
by Ravisara Vathagavorakul, Tomohiro Gonjo, Miwako Homma
The aim of this study was to compare artistic swimmers (ASs) and water polo players (WPs) in their polyrhythmic production ability and entrainment between arm and leg motion frequency. Nine ASs and nine WPs participated in the study. First, we assessed the natural eggbeater kick frequency of each participant without any additional motion for 20 s. We then required the participants to perform a circular arm movement in synchronization... Читать дальше...
by Jee Hee Yoon, Min Ji Jeon, Mijin Kim, A. Ram Hong, Hee Kyung Kim, Dong Yeob Shin, Bo Hyun Kim, Won Bae Kim, Young Kee Shong, Ho-Cheol Kang
Читать дальше...
by Alberto Alonso-Fernández, Nuria Toledo-Pons, Borja G. Cosío, Aina Millán, Néstor Calvo, Luisa Ramón, Sara Hermoso de Mendoza, Daniel Morell-García, Josep Miquel Bauça-Rossello, Belén Núñez, Jaume Pons, Juan A. Palmer, Luisa Martín, María Peñaranda, Joan A. Pou, Jaume Sauleda, Ernest Sala-Llinas
Читать дальше...
by Alyssa R. Martin, Aida Sivro, Zoe R. Packman, Eshan U. Patel, Livia R. Goes, Lyle R. McKinnon, Jacquie Astemborski, Gregory D. Kirk, Shruti H. Mehta, Claudia Cicala, James Arthos, Andrew D. Redd, Thomas C. Quinn
Читать дальше...
by Natasha N. Gebhart, Richard W. Hardy, Kevin J. Sokoloski
The identification of host / pathogen interactions is essential to both understanding the molecular biology of infection and developing rational intervention strategies to overcome disease. Alphaviruses, such as Sindbis virus, Chikungunya virus, and Venezuelan Equine Encephalitis virus are medically relevant positive-sense RNA viruses. As such, they must interface with the host machinery to complete their infectious lifecycles. Nonetheless... Читать дальше...
by The PLOS ONE Editors
by Ramesh B. Kasetti, Pinkal D. Patel, Prabhavathi Maddineni, Gulab S. Zode
by Khalid Bashir, Inaamul Haq, S. Muhammad Salim Khan, Mariya Amin Qurieshi
Читать дальше...
by Jennifer S. Lord, Rachel S. Lea, Fiona K. Allan, Mechtilda Byamungu, David R. Hall, Jessica Lingley, Furaha Mramba, Edith Paxton, Glyn A. Vale, John W. Hargrove, Liam J. Morrison, Stephen J. Torr, Harriet K. Auty
Читать дальше...
by Miho Sassa, Evans A. Chadeka, Ngetich B. Cheruiyot, Mio Tanaka, Taeko Moriyasu, Satoshi Kaneko, Sammy M. Njenga, Sharon E. Cox, Shinjiro Hamano
Читать дальше...
by Edy F. Pereira, Gregory Gegembauer, Marilene R. Chang, Zoilo P. de Camargo, Thiago F. Nunes, Sergio M. Ribeiro, Lídia R. de Carvalho, Bianca M. Maldonado, Rinaldo P. Mendes, Anamaria M. M. Paniago
Читать дальше...
by Habtye Bisetegn, Ayalew Jejaw Zeleke, Endalamaw Gadisa, Girma Shumie, Demekech Damte, Tiruework Fenta, Sinkinesh Behaksra, Abebe Genetu Bayih
Читать дальше...
by Andrew Lawson, R Boaz III, A. Corberán-Vallet, Marcos Arezo, Edmundo Larrieu, Marco A. Vigilato, Victor J. Del Rio Vilas
Читать дальше...
by Jihène Bettaieb, Amine Toumi, Wissem Ghawar, Sadok Chlif, Mariem Nouira, Nabil Belhaj-Hamida, Adel Gharbi, Nissaf Ben-Alaya, Dhafer Laouini, Hechmi Louzir, Koussay Dellagi, Afif Ben Salah
Читать дальше...
by Lilani Karunanayake, Chandika D. Gamage, Chandima P. Gunasekara, Sajiv De Silva, Hidemasa Izumiya, Masatomo Morita, Devinda S. Muthusinghe, Kumiko Yoshimatsu, Roshan Niloofa, Panduka Karunanayake, Wimalasiri Uluwattage, Makoto Ohnishi, Nobuo Koizumi
Читать дальше...
by Jing Chen, Jonas Bacelis, Pol Sole-Navais, Amit Srivastava, Julius Juodakis, Amy Rouse, Mikko Hallman, Kari Teramo, Mads Melbye, Bjarke Feenstra, Rachel M. Freathy, George Davey Smith, Deborah A. Lawlor, Jeffrey C. Murray, Scott M. Williams, Bo Jacobsson, Louis J. Muglia, Ge Zhang
Читать дальше...
by Thareendra De Zoysa, Eric M. Phizicky
All tRNAs are extensively modified, and modification deficiency often results in growth defects in the budding yeast Saccharomyces cerevisiae and neurological or other disorders in humans. In S. cerevisiae, lack of any of several tRNA body modifications results in rapid tRNA decay (RTD) of certain mature tRNAs by the 5’-3’ exonucleases Rat1 and Xrn1. As tRNA quality control decay mechanisms are not extensively studied in other eukaryotes, we studied... Читать дальше...
by Shelbi L. Russell, Evan Pepper-Tunick, Jesper Svedberg, Ashley Byrne, Jennie Ruelas Castillo, Christopher Vollmers, Roxanne A. Beinart, Russell Corbett-Detig
Читать дальше...
by Brian Onken, Natallia Kalinava, Monica Driscoll
High glucose diets are unhealthy, although the mechanisms by which ikelevated glucose is harmful to whole animal physiology are not well understood. In Caenorhabditis elegans, high glucose shortens lifespan, while chemically inflicted glucose restriction promotes longevity. We investigated the impact of glucose metabolism on aging quality (maintained locomotory capacity and median lifespan) and found that, in addition to shortening lifespan... Читать дальше...
by Yizhuo Zhou, Pedro N. Pozo, Seeun Oh, Haley M. Stone, Jeanette Gowen Cook
Читать дальше...
by Leandro José de Assis, Lilian Pereira Silva, Li Liu, Kerstin Schmitt, Oliver Valerius, Gerhard H. Braus, Laure Nicolas Annick Ries, Gustavo Henrique Goldman
Читать дальше...
by Lucia Simonicova, W. Scott Moye-Rowley
Azole drugs are the most frequently used antifungal agents. The pathogenic yeast Candida glabrata acquires resistance to azole drugs via single amino acid substitution mutations eliciting a gain-of-function (GOF) hyperactive phenotype in the Pdr1 transcription factor. These GOF mutants constitutively drive high transcription of target genes such as the ATP-binding cassette transporter-encoding CDR1 locus. Previous characterization of Pdr1 has demonstrated... Читать дальше...
by Claudia Bachmann, Tom Tetzlaff, Renato Duarte, Abigail Morrison
The impairment of cognitive function in Alzheimer’s disease is clearly correlated to synapse loss. However, the mechanisms underlying this correlation are only poorly understood. Here, we investigate how the loss of excitatory synapses in sparsely connected random networks of spiking excitatory and inhibitory neurons alters their dynamical characteristics. Beyond the effects on the activity statistics, we find that the loss... Читать дальше...