The US central bank has held interest rates at the highest levels in more than two decades to bring inflation down to its long-term two percent target without doing too much damage to either the labour market or the broader economy.
After years of focusing primarily on inflation, Federal Reserve officials have now turned their attention increasingly to the labour market, which has shown some signs of weakness in recent months despite remaining strong overall.
Traders will be keenly watching Powell's remarks to Congress on Tuesday and Wednesday for any indications of when the Fed will start cutting rates.
The Fed chair last week fanned hopes of a cut, saying the battle against inflation had made "progress" and the job market was cooling.
"We expect Powell to reiterate the need to see more evidence of slowing inflation before cutting interest rates. But with the recent signs of softer growth and labour market, markets will closely watch if Powell gives any hints on the timing of rate cuts," said Carol Kong at Commonwealth Bank of Australia.
"The Fed Funds futures market has currently attached almost an 80 percent chance of the first rate cut in September," she said.
Investors are also looking to US consumer inflation data due Thursday for further indications that price increases are still easing as hoped, which would give the Fed greater confidence to start cutting rates.
"Powell is expected to hint at possible rate cuts starting in September if inflation continues to decline. A softer core CPI print would likely support this outlook, keeping the US dollar on a weaker trajectory," said Luca Santos, market analyst at ACY Securities.
Wall Street's main indices mostly advanced on Monday, with the S&P 500 and Nasdaq both reaching new records.
The optimistic mood continued into Asia, with Tokyo up more than one percent while Sydney, Seoul, Singapore, Taipei, Bangkok, Kuala Lumpur and Jakarta were all higher.
Hong Kong and Shanghai were lower ahead of a key policy meeting in China next week.
US Treasury bond yields, which are closely watched as a proxy for interest rates, were little changed.
On forex markets the euro was flat against the dollar Tuesday following the inconclusive outcome of France's snap elections, with the single currency trading at $1.0827.
"Following the recent French elections, political uncertainty remains high, yet the euro has shown remarkable stability during the Asian trading session," said Santos, with its narrow trading range "reflecting a muted market response".
Key figures around 0245 GMT
Tokyo - Nikkei 225: UP 1.4 percent at 41,342.44 points
Hong Kong - Hang Seng Index: DOWN 0.4 percent at 17,450.33
Shanghai - Composite: DOWN 0.4 percent at 2,911.053
Euro/dollar: FLAT at $1.0827 from $1.0827 at 2030 GMT on Monday
Euro/pound: UP at 84.55 pence from 84.50 pence
Dollar/yen: UP at 160.99 yen from 160.80 yen
Pound/dollar: DOWN at $1.2806 from $1.2810
West Texas Intermediate: DOWN 0.3 percent at $82.09 per barrel
Brent North Sea Crude: DOWN 0.2 percent at $85.54 per barrel
New York - Dow: DOWN 0.1 percent at 39,344.79 points (close)
London - FTSE 100: DOWN 0.1 percent at 8,193.49 (close)
burs-mtp/sco
